RIGHT INGREDIENTS

CLINICAL RESEARCH

Dolichos Biflorus Seed And Betel (Piper Betle) Leaf Extract (LOWAT™)

• Sengupta K, Mishra A, Rao M, et al. Efficacy of an Herbal Formulation LI10903F Containing Dolichos Biflorus and Piper Betle Extracts on Weight Management. Lipids in Health and Disease, 2012, 11:176.

Subjects taking this ingredient at the same dosage as in RealDose Weight Loss Formula No. 1:

• Lost an average of 9.4 lbs vs. 3.9 lbs for those taking a placebo (2.4X better weight loss results).
• Experienced a 15.3% increase in serum Adiponectin concentration. Elevated Adiponectin is associated with increased fat metabolism.
• Experienced a 17.3% decrease in serum Ghrelin concentration. Decreased Ghrelin is associated with a reduction in hunger.

• Chatterjee A, Fernandez C, Khandalavala B, et al. Efficacy and Safety Evaluation of a Novel Weight Management Herbal Formulation LOWAT. 51st Annual Meeting, American College of Nutrition, New York, NY Oct 7-9, 2010. Poster Presentation.

Decaffeinated Green Coffee (Coffea canephora) (seed) standardized to 50% total polyphenols, 45% total chlorogenic acids, 10% 5-caffeoylquinic acid (Svetol™)

• Dellalibera O, Lemaire B, Lafay S. Svetol, Green Coffee Extract, Induces Weight Loss and Increases the Lean to Fat Mass Ratio in Volunteers with Overweight Problem. Phytotherapie, 2006; 4: 1-4.

Subjects taking this ingredient at the same dosage as in RealDose Weight Loss Formula No. 1:

• Lost an average of 10.9 lbs vs. 5.4 lbs for those taking a placebo (2X better weight loss results).
• Increased their muscle to fat ratio by 4.1% vs. 1.6% for those taking a placebo.

• Henry-Vitrac C, Ibarra A, Roller M, et al. Contribution of Chlorogenic Acids to the Inhibition of Human Hepatic Glucose-6-phosphatase Activity in Vitro by Svetol, a Standardized Decaffeinated Green Coffee Extract. Journal of Agricultural and Food Chemistry, 2010; 58: 4141-4144. 270% more than in regular coffee beans.

Siberian Rhodiola Rosea (root) extract standardized to 3% rosavins, 1% salidroside

• Brown RP, Gerbarg PL, Ramazanov. Rhodiola Rosea: A Phytomedicinal Overview. HerbalGram, 2002.

• Ramazanov Z, Jimenez del Rio M, Letchamo W. Standardized Rhodiola Rosea, A Unique Phytomedicine: A Current Phytochemical Quality Overview. Proceedings of 8th International Congress Phytopharm - 2004, Mikkeli, Finland 21-23 June 2004.

Pepper (Piper nigrum) (fruit) standardized to minimum 95% piperine (BioPerine™)

• Badmaev V, Majeed M, Prakash L. Piperine Derived from Black Pepper Increases the Plasma Levels of Coenzyme Q10 Following Oral Supplementation. The Journal of Nutritional Biochemistry, Feb 2000; 11: 109-113.

• Badmaev V, Majeed M, Norkus E. Piperine, An Alkaloid Derived from Black Pepper Increases Serum Response of Beta-Carotene During 14-Days of Oral Beta-Carotene Supplementation. Nutrtion Research, 1999; 19(3): 381-388.